Searchable abstracts of presentations at key conferences in endocrinology

ea0026p52 | Endocrine disruptors | ECE2011

Phytoestrogen genistein causes downregulation of oestrogen receptor α in uterus of female Sprague Dawley rats

Md Zin Siti Rosmani , Kassim Normadiah M , Omar Siti Zawiah

Phytoestrogen genistein is one of the endocrine disrupting chemicals found mostly in soybean. It has become a topic of interest since decades ago in view of its benefits in reducing the risks of breast cancer, cardiovascular disease, obesity and perimenopausal symptoms. However, it has been reported that genistein can cause adverse consequences on female reproductive system and may cause infertility. Its action was said to be associated with its binding affinity to oestrogen r...